| Lana Santorelli Gallery | 110 W 26th St, Ground Floor, New York (Chelsea) |
| Julie Saul Gallery | 535 W 22nd St, 6th Fl, New York (Chelsea) |
| Schaller + Jaquish Art Projects | 547 W 27th St, #529, New York (Chelsea) |
| Edition Schellmann | 210 11th Ave, 8th Fl, New York (Chelsea) |
| Lucas Schoormans Gallery | 508 W 26th St, #11B, 11th Fl, New York (Chelsea) |
| Schroeder Romero | 637 W 27th St, New York (Chelsea) |
| Howard Scott Gallery | 529 W 20th St, 7th Fl, New York (Chelsea) |
| Sears-Peyton Gallery | 210 11th Ave, #802, New York (Chelsea) |
| Sebastian + Barquet | 544 W 24th St, New York (Chelsea) |
| Senior & Shopmaker | 21 East 26th St, 2nd floor, New York (Chelsea) |
| SEPIA International | The Alkazi Collection | 148 W 24th St, 11th Fl, New York (Chelsea) |
| Serrano Contemporary / Sonnet Gallery | 547 W 27th St, #514, New York (Chelsea) |
| Tony Shafrazi Gallery | 544 W 26th St, New York (Chelsea) |
| Jack Shainman Gallery | 513 W 20th St, New York (Chelsea) |
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| Paul Sharpe Contemporary Art | 525 W 29th St, 2nd Fl, New York (Chelsea) |
| 547 W 27th St, 5th Fl, New York (Chelsea) |
| Susan Sheehan Gallery | 535 W 22nd St, 3rd Fl, New York (Chelsea) |
| Allen Sheppard Gallery | 530 W 25th St, New York (Chelsea) |
| Sikkema, Jenkins & Co | 530 W 22nd St, New York (Chelsea) |
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| Bruce Silverstein | 529 W 20th St, 3rd Floor, New York (Chelsea) |
| 535 W 24th St, Ground Floor, New York (Chelsea) |
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| Skoto Gallery | 529 W 20th St, 5th Fl, New York (Chelsea) |
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| Gary Snyder Project Space | 250 W 26th St, 4th Floor, New York (Chelsea) |
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| SOHO20 Chelsea Gallery | 547 W 27th St, #301, New York (Chelsea) |
| Sonnabend | 536 W 22nd St, New York (Chelsea) |
| Sperone Westwater | 415 W 13th St, 2nd Fl, New York (Chelsea) |
| Sputnik Gallery | 547 W 27th St, #518, New York (Chelsea) |
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| Sragow Gallery | 153 W 27th St, #505, New York (Chelsea) |
| Robert Steele Gallery | 511 W 25th St, Suite 101 (Moving in June/July Upstairs same building), New York (Chelsea) |
| Michael Steinberg Fine Art | 526 W 26th St, #215, New York (Chelsea) |
| Maya Stendhal Gallery | 545 W 20th St, New York (Chelsea) |
| John Stevenson Gallery | 338 W 23rd St, New York (Chelsea) |
| Stricoff Fine Art, Ltd. | 564 W 25th St, New York (Chelsea) |
| Stux Gallery | 530 W 25th St, New York (Chelsea) |
| SVA - School of Visual Arts | 141 W 21st St, New York (Chelsea) |
| 601 W 26th St, 15th Fl, New York (Chelsea) |